Ozone therapy
Ozone therapy and cancer
Ozone (O3) is a gas which is formed naturally from oxygen through the action of ultraviolet light and electrical discharges as in an electric storm. For medical use, it is produced in generators by passing oxygen through a high voltage gradient, the gas produced being a mixture of oxygen and ozone.
This study says: The results obtained in this study have demonstrated the potentialities of ozone as an antimetastatic agent, as well as an adjuvant for the treatment of cancer patients.
This study found that in patients with delayed healing following tumor surgery, the local application of ozone, in conjunction with other standard treatments, could accelerate the healing process …
This 2025 Systematic Review of 16 studies concluded: medical ozone treatment represents a promising complementary approach for managing specific cancer-related symptoms, particularly pain, fatigue, anxiety, and depression, with a favorable safety profile when administered within established guidelines.
This 2024 Integrative Literature Review looked at 14 studies and found: Ozone therapy is a promising complementary treatment option for breast cancer. In 1980, Sweet et al reported that ozone therapy was effective for treating breast cancer. The presence of ozone at a concentration of 0.3 to 0.5 parts per million inhibited cancer cell growth by 40% and 60%, respectively, and at a concentration of 0.8 parts per million, cancer cell growth was inhibited by more than 90% compared with 50% inhibition in normal cells.
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In 2001, Kontorshchikova et al enrolled 32 patients with breast cancer in a clinical trial. The patients received ozone therapy and the results confirmed that ozone therapy decreased the incidence and degree of cytostatic toxicity, improved the quality of life, and immunological parameters, and significantly increased the activity of the antioxidant defense system.
In 2012, Alekberov and Potanin reported the use of ozone therapy in patients with breast cancer who underwent breast reconstruction. A total of 151 patients were enrolled, of whom 71 were given ozone therapy in the form of an ozone-oxygenated crystalloid solution. After ozone therapy, the oxygen tension in the tissues and blood increased, blood flow normalized, and the blood lymphocytes were more rapidly restored after breast reconstruction surgery. Furthermore, in patients who received ozone therapy, the frequency of early postoperative complications such as necrosis of the autotransplant, was 2.5 times lower than that in patients who did not receive ozone-oxygenated crystalloid solution.
At an appropriate dose, ozone does not induce toxic effects on the cells of normal tissue because the antioxidant system of the cells can typically handle mild ozone-induced injury; however, at high concentrations, it may cause serious side effects, including respiratory and vascular effects, allergic reactions, hemolysis, and transient oxidative stress.
This 2024 study says: High-dose ozone therapy represents a promising complementary approach in oncology, particularly for its potential to reduce the toxicity of conventional therapies, improve tumor oxygenation, and support immune function. This dual action of direct tumor cytotoxicity through oxidative stress and indirect modulation of the immune response makes ozone an appealing candidate in integrative cancer care.
The existing literature indicates that ozone therapy can improve treatment tolerance and patient quality of life…
Ozone Treatments at Oasis of Hope Hospital
Source: Oasis of Hope hospital
The benefits derived from this therapy are staggering. For example, Oasis doctors know that ozonation of the blood improves the exchange of oxygen in the blood, activates the immune system, and increases the efficiency of the antioxidant system. But what is most exciting to us is how these three activities combine to effectively retard or reverse tumor growth.
Over the last seventeen years, doctors at Oasis have advanced the use of ozone therapy, and the results have been extraordinary. Our patients have experienced measurable tumor reduction quickly, sometimes in as little as two weeks for long-term results, we still believe that slower acting metabolic therapy is vital, but it is wonderful to get fast results too. Indeed, ozone provokes a cascade of effects when it is introduced into the bloodstream.
Page updated February 2026