Bone Cancer

Bone Cancer

General Information About Ewing Sarcoma

KEY POINTS

  • Ewing sarcoma is a type of tumor that forms in bone or soft tissue.
  • Undifferentiated round cell sarcoma may also occur in the bone or soft tissue.
  • Signs and symptoms of Ewing sarcoma include swelling and pain near the tumor.
  • Tests that examine the bone and soft tissue are used to diagnose and stage Ewing sarcoma.
  • A biopsy is done to diagnose Ewing sarcoma.
  • Certain factors affect prognosis (chance of recovery).

Read the full article on the National Cancer Institute website.


General Information About Osteosarcoma and Malignant Fibrous Histiocytoma of Bone

KEY POINTS

  • Osteosarcoma and malignant fibrous histiocytoma (MFH) of the bone are diseases in which malignant (cancer) cells form in bone.
  • Having past treatment with radiation can increase the risk of osteosarcoma.
  • Signs and symptoms of osteosarcoma and MFH include swelling over a bone or a bony part of the body and joint pain.
  • Imaging tests are used to detect (find) osteosarcoma and MFH.
  • A biopsy is done to diagnose osteosarcoma.
  • Certain factors affect prognosis (chance of recovery) and treatment options.

Read the full article on the National Cancer Institute website.


Latest Treatments Updates

PQQ (Pyrroloquinoline quinone)
PQQ is a natural compound found in a variety of foods. It acts as an antioxidant and supports healthy mitochondrial function.

This study says: Chondrosarcoma is the second most commonly occurring primary bone malignancy, which affects the pelvis, long bones and the spine, in addition to the larynx, head and neck, and it eventually metastasizes. Currently, chondrosarcoma remains largely incurable due to poor prognosis and a high rate of recurrence.The present study examined cell death following treatment with or without different concentrations of PQQ in cancer and normal cells. It was identified that cell death increased in a dose- and time-dependent manner following treatment with PQQ, while the effect on normal cells was relatively small.

In conclusion, the mechanism underlying PQQ-induced apoptosis may be associated with increasing the levels of ROS, suggesting that PQQ may be a potential drug for chondrosarcoma therapies.

Widely available as a supplement.


 

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