Treatment side effects

Standard Cancer Treatments side effects

 
The cancer industry claims that standard treatments are “highly effective” while  downplaying the painful and sometimes lethal side effects. Here’s a quick look at some of the facts.

Surgery
Radiation
Chemotherapy

SURGERY

Possible complications for any surgical procedure include:

  • Complications related to anesthesia, including pneumonia, blood clots and, rarely, death
  • Infection at the incision site, which may worsen scarring and require additional surgery
  • Fluid build up under the skin
  • Mild bleeding, which may require another surgical procedure, or bleeding significant enough to require a transfusion
  • Obvious scarring or skin breakdown, which occurs when healing skin separates from healthy skin and must be removed surgically
  • Numbness and tingling from nerve damage, which may be permanent
    Source: Mayo Clinic

Atrial fibrillation after surgery increases risk of heart attacks, strokes.
An irregular heartbeat following surgery known as post-operative atrial fibrillation (POAF) often is dismissed as a transient phenomenon. But a study has found that POAF can significantly increase the risk of heart attack or stroke during the first 12 months after surgery.
Source: Science Daily / University of Toronto

A study (The efficacy of surgical treatment of breast cancer.) found:
The conclusion from the previous analysis, that surgery has not been shown to reduce mortality for any form of cancer, is therefore still valid.

A study (The efficacy of surgical treatment of cancer – 20 years later) published in 2014 concluded:
Caution: No benefits can be expected to be achieved from using cancer surgery except in a few immediately life-threatening situations. Surgery appears to be based on an invalid paradigm of what cancer is. Cancer appears to be a systemic disease and therefore standard treatments need to be reassessed in this light.


The following is published on the respected website canceractive.com

Biopsies and surgery can and do spread cancer cells

For a long time there have been rumblings about the possible dangers of cancer spread when having biopsies, for example, in breast cancer or prostate cancer. The issue is called seeding. Namely that when a needle is used up to 15 times to take samples across an area, it might hit an area of cancer on probe 3 and pass just a few cells on when probing all the following areas.

Just such an article appeared in the BMJ (July 2004) quoting a report from Australian surgeons whose stated view was that continuing liver biopsies gave rise to a serious risk of seeding and stating that such biopsy was useless and dangerous.

Surgery can make cancers grow faster

  • Life Extension Magazine in America reported as early as 1985 that cancer surgery increased the risk of metastases. By 2001 the British Journal of Cancer contained an article stating that removal of the primary tumour may result in sudden acceleration of the metastatic process. By 2009 in the Annals of Surgery, researchers reported that cancer surgery itself can create an environment in the body that greatly lessens the obstacles to metastases. This corroborates observations that relatively soon after surgery, metastatic lesions quickly emerge that were not necessarily evident prior to the surgical procedure Bill Fallon, Life Extension magazine.
  • In icon [Integrative Cancer and Oncology News magazine] we covered Italian Breast cancer research by Dr Romano Demicheli, which looked at women having mastectomies at the Milan Cancer Institute. The conclusion made was that some women relapsed quickly and the surgery had created biochemical changes actually promoting cancer cell and blood supply growth, and increasing tumour growth rates.

Ways surgery encourages cancer spread

Apart from physically disturbing and releasing cancer cells around the body, other cancer-proliferating activities happen with surgery.

  • Surgery involves fundamental biochemical changes in the body, from the effects of stress to inflammatory response to the production of healing hormones. On top of that, Doctors give you drugs at the same time – anaesthetics and antibiotics. You simply cannot think of surgery as an isolated incident in the body.
  • Anyway, your cancer may well not be an isolated island in your body. Far more likely is that the conditions of cancer exist all over your body. Research covered in icon Cancer Watch have shown that cancers produce secondary pre-cancer cells much earlier than previously thought. These rogue cells pass round the body to other tissues where they and their oncogenes lie dormant.
  • Research has also shown that tumours actually produce chemicals that stop vascular growth to these dormant cancer cells lying in other parts of the body. In other words the cancer cells need a blood supply in order to grow into a tumour but the main primary tumour actually stops rivals forming. Remove the primary and the others can come out to play. A great deal of research has focused on Vascular Endothelial Growth Factor (VEGF). You can suppress VEGF with bioactive natural compounds like curcumin, green tea (EGCG), resveratrol, milk thistle and genistein (in soy and red clover).
  • Indeed, the actual healing process from any surgery see an increase in growth hormone levels in the body. Major surgery will produce a large growth hormone response. (This is one reason why I believe strongly that people with cancer should not touch one drop of mass market cows´ dairy. Because of the way the cows are kept, it increases blood levels of IGF-1, a growth hormone). Surgeons know this and have been trying to minimise surgery – for example using more lumpectomies or key hole surgery.
  • Surgery can cause localised inflammation through eicosanoids, short-lived but highly active hormones. Especialy if steroids are used at the same time. Cancer likes inflammation, it encourages its spread. Omega-3 from fish oil, a small aspirin, ginger, garlic, aloe vera, curcumin, and resveratrol can reduce the inflammation in the body. (Vane and others)
  • The antibiotics and drugs administered will damage your microbiome, the crucial bacteria in your gut that control your immune system, and keep pathogens and yeasts in check. Friendly bacteria in your microbiome also produce your B vitamins, vitamin K that protects your liver and short-chain esters that prevent build up of bad triglycerides and inflammatory compounds in the blood stream. We suggest you read our article ´Heal Ur Gut´ with some urgency and take probiotics and B complex during the period of the surgery.
  • The antibiotics and drugs actually reduce plasma levels of vitamin D. Yet it is known that people with cancer and low levels of vitamin D, survive least. Take 5000 IUs per day of vitamin D, at least.
  • Surgery uses anaesthetic., which is also known to reduce the immune system via the gut microbiome. Doctors typically measure the white cell count, but as we continually point out, there are many different types of white cells (T-cells, B-cells, macrophages etc). Research has shown that surgery greatly reduces the numbers of Natural Killer (NK) cells circulating in the blood you will have a much harder job to kill off a cancer cell after surgery. Readers will know that we have always advocated going into surgery with a strong immune system we have suggested a combination of astragalus, cats claw, turmeric, echinacea, total natural vitamin E, zinc, selenium, grape seed extract and natural vitamin C with bioflavenoids. Vitamins D and K have also been shown to help fight cancer cells in research.
  • The drugs and anaesthetic used during surgery, and the stress involved, can make the body more acidic. Cancer tumours are highly acidic. Research from Arizona, Chicago and H. Lee Moffitt has shown that acid conditions in the body increase metastases from tumours and that acidic conditions favour these metastatic cells ´taking hold´ and forming new tumours.

How to prepare for cancer surgery naturally

Source: CancerActive.com

Ten ways to prepare for surgery: Surgery can be daunting but there are definitely things you can do to manage your way through it without major issues and side-effects.

  1. Prior to surgery you may be advised to change your diet. You should certainly aim to lose a little excess weight if you have it, and eat healthily. Avoid sugar and bad saturated fat, which both compromises the immune system, avoid alcohol, quit smoking and instead nourish yourself with plenty of fruit, vegetables, nuts and seeds and olive oil and fish oils.
  2. Consider doing yoga to encourage core strength and calm your body. In the USA, research from the New York Presbyterian Hospital showed that those patients who meditated before surgery lost 40% less blood than those who did not.
  3. Be clear what your surgery entails, how long it lasts, likely side- effects, the medications you will be given and will need afterwards.
  4. The antibiotics you will surely have will make a major dent in the volume of your good gut bacteria; you may even lose certain strains forever. With the good bacteria compromised, both yeasts and pathogen levels will rise. These can compromise your immune system, increase toxin levels, cause fatigue, gut issues, mouth ulcers and more.
           a.
    Two days after the operation start to take a yeast killer such as Oregano oil (300 mg) – as a pill or by rubbing Essential Oil on your wrists. Continue this for 8-12 weeks.
           b. Also take Artemisinin (Sweet Wormwood), 200 mg a day before bed for 10 days. Then have 10 days off, and repeat. In all take artemisinin for 5 rounds of 10 days on, 10 days off.
  5. Take a Total Vitamin E – all 4 tocopherols and all 4 tocotrienols – to help you heal quicker. It is also an antibiotic. Take from two weeks before until about 6 weeks after. It works!
  6. Take a multi-strain probiotic before and after surgery.
  7. Buy some Aloe Vera gel 99.9% pure (or use the real thing if you grow it!). After the would has joined, you can gently rub it on the scars – it acts to kill microbes and it will help you heal better, and reduce scaring.
  8. Will you be in pain after the operation and for how long. Consider alternative pain relief rather than taking yet more drugs. Hemp oil with at least 60% CBD content has been approved as pain relief.
  9. Remember there are natural compounds that can really help post-operation.
         a.
    Bioactive compounds like pau d’arco, garlic, ginger root, goldenseal/berberine, cloves, probiotics can attack and kill infections. You don’t have to have more drugs.
          b. Natural compounds like echinacea, cat’s claw, astragalus, essiac will boost the immune system.
          c. Melatonin, ashwagandha, frankincense are natural anti- inflammatory compounds.
          d. Foods such as olive oil, fish oils, berries, apples, carrots, chicory, onions, and red grapes can boost good gut bacteria and in turn boost the immune system.
          e. There is some research showing arnica and bromelain can reduce swelling and bruising. You can take before and after surgery.
  10. About 6 weeks afterwards, start eating probiotic foods to replenish lost gut bacteria more quickly – a little unpasteurised cheese, kefir products (UK – Chuckling goat), apple cider vinegar, sauerkraut, kombucha, kempeh.

RADIATION

Important Safety Statement: Most side effects of radiotherapy, including radiotherapy delivered with Accuray systems, are mild and temporary, often involving fatigue, nausea, and skin irritation. Side effects can be severe, however, leading to pain, alterations in normal body functions (for example, urinary or salivary function), deterioration of quality of life, permanent injury and even death.
Source: Accuray (manufacturer of radiation therapy equipment)

Radiation side effects

  • Cell damage that leads to new cancer.
  • Diarrhea
  • Fatigue
  • Hair loss
  • Mouth and throat changes
  • Nausea and vomiting
  • Problems around sexuality and fertility in men
  • Problems around sexuality and fertility in women
  • Skin changes
  • Urination changes
    Source: The website of the National Cancer Institute (http://www.cancer.gov)

Radiation therapy to the chest can cause:

  • Lung damage (scarring, inflammation, breathing difficulties)
  • Heart damage (scarring, inflammation, coronary heart disease)
  • Osteosarcoma (bone cancer)
  • Breast cancer
  • Thyroid cancer
  • Hypothyroidism or hyperthyroidism
    Source: Leukemia and Lymphoma Society

Study: Intensity-modulated radiation therapy, protons, and the risk of second cancers
Intensity-modulated radiation therapy (IMRT) allows dose to be concentrated in the tumor volume while sparing normal tissues. However, the downside to IMRT is the potential to increase the number of radiation-induced second cancers
…Intensity-modulated radiation therapy may double the incidence of solid cancers in long-term survivors.

Source: International Journal of Radiation Oncology


Managing Radiation Therapy Side Effects

Source: National Cancer Institute

Skin Care:

■       Look at the list of skin products on the back of this sheet. Ask your doctor or nurse which ones are okay for you to use.

Protect your skin.

■       Make sure your clothing covers the area being treated when you are outside.

■       Wear clothes that are loose.

■       Choose clothes and bed sheets made of soft cotton.

■       Use an electric razor if your doctor or nurse says you can shave.

Care for your skin.

■      Shower or bathe with warm, not hot, water. Don’t shower more than one time a day.

■      If you bathe, limit baths to two times a week. Bathe for less than 30 minutes.

■      Gently pat your skin dry after showers or baths.

■      Don’t rub off the markings your radiation therapist made on your skin. They show where to place the radiation.

■      Don’t use heating pads, ice packs, or bandages on the area getting radiation.

■      Don’t use tanning beds.

■      Check with your doctor or nurse before you put anything on your skin.

Watch out for a more serious skin problem (moist reaction).

If your skin hurts in the area where you get treatment, tell your doctor or nurse. Your skin might have a moist reaction. Most often this happens in areas where the skin folds, such as behind the ears or under the breasts. It can lead to an infection if not properly treated. Ask your doctor or nurse how to care for these areas.

Tell your doctor or nurse if your skin stays wet or if you have sores.

Feeling Sick and Throwing Up (Nausea and Vomiting)

What are nausea and vomiting?

Nausea is when you feel sick to your stomach, like you are going to throw up. Vomiting is when you throw up.

■   Drink enough liquids each day to prevent dehydration (loss of too much water from the body).

■   Ask your doctor or nurse about medicine that will help. Learn how you should take the medicine.

Take these steps to feel better:

Take your anti-nausea medicine.

■■ Talk with your doctor or nurse about the best times and ways to take your medicine.

■■ Tell your nurse if the medicine is not helping. There are different kinds of medicine, and one may work better than another for you.

Try tips to settle your stomach.

■■ Eat foods that are easy on your stomach. See the list on the other side of this sheet.

■■ Eat 5 to 6 small meals instead of 3 large meals each day.

■■ Eat and drink slowly.

■■ Don’t lie down right after eating.

Instead, sit up for a while.

Avoid some foods.

■■ Don’t eat greasy, fried, or spicy foods if you feel sick after eating them.

■■ Don’t eat foods that are too hot or too cold if they make you sick to your stomach.

■■ If the smell of food bothers you, ask others to cook for you. Then let the food cool down before you eat it.

Try these tips on treatment days:

■■ Learn the best time for you to eat and drink. Some people find that it helps to eat a small snack before treatment. Others avoid eating or drinking right before treatment because it makes them feel sick.

■■ Listen to music or an audiobook before treatment, to help relax.

Questions to ask your doctor or nurse:

■   What problems should I call you about?

■   How should I take the medicine to prevent nausea and vomiting?

■   How much liquid should I drink each day?

■   What foods should I eat?

■   What foods should I avoid or have less of?

■   Could you give me the name of someone who can tell me about acupuncture and other things that may help prevent nausea?

Take good care of your mouth.

Before treatment:

■      Visit a dentist at least 2 weeks before your first treatment. Tell the dentist that you will be having radiation therapy.

During treatment:

■      Check inside your mouth every day and look for any changes.

■      Brush your teeth, gums, and tongue gently with a soft, clean toothbrush.

■      Brush after each meal and before bedtime.

■      Sip water or suck on ice chips to keep your mouth and throat wet.

Every 1 to 2 hours during the day:

■      Rinse your mouth with a mixture of 1 cup warm water, 1/4 teaspoon baking soda, and 1/8 teaspoon salt. Swish the mixture around in your mouth, and then spit it out.

■      Ask your doctor or nurse to write down any other mouth rinses that you should use.

Tips to make eating more comfortable:

This can help:

■      Mash food or cut it into small pieces.

■      Add gravy or broth to make other foods wet and soft.

■      Drink through a straw if that helps.

■      Eat foods warm—not too hot.

■      Eat soft foods, such as cooked cereals, macaroni, mashed potatoes, scrambled eggs, and yogurt.

■      Use a blender to make milkshakes or blend your food.

Stay away from these:

■      Don’t drink alcohol or sour juices.

■      Don’t eat foods that are spicy, salty, or have a lot of sugar. Hard, sharp foods such as chips can also make your mouth hurt.

■      Don’t use tobacco—no cigarettes, pipes, cigars, or chewing tobacco.

Tips to help with pain or burning in your throat:

■      Sit upright and bend your head forward a little when you are eating or drinking.

■      Sit or stand up for at least 30 minutes after eating.

Tell your doctor or nurse if you have trouble swallowing, feel like you are choking, or cough while you are eating or drinking.

Questions to ask your doctor or nurse:

1.      What mouth or throat problems should I call you about?

2.      Can you show me how to make a mouth rinse?

3.      What medicine can I take to help stop the pain?

Feeling Weak or Tired (Fatigue)

Did you know that most people getting radiation therapy feel very tired?

■      Fatigue does not mean that the cancer is getting worse.

■      Fatigue does not mean that the treatment is not working.

■      Feeling tired is normal during this time.

You may feel a little tired or very tired during radiation therapy.

Try some of the tips below:

They have helped others. Talk with your doctor or nurse about other things you can do to have more energy.

Be active if you can.Most people feel better when they exercise each day. Some people even sleep and eat better when they exercise.

■      Walk for 15 to 30 minutes each day.

■      Take a short bike ride or ride an exercise bike.

■      Choose an exercise or sport that you enjoy.

Do fewer things. Ask for help when you need it. You may have times of high and low energy.

■      Do the activities that are most important to you first.

■      Ask family and friends for help. They can make meals, drive you to the doctor, or help in other ways.

■      Learn your limits. Don’t fill your day with too many activities.

Plan a work schedule that is right for you. Some people feel well enough to work. Others need to cut back.

■      Take medical leave if you need to.

■      Ask your boss if you can work from home.

Plan time to rest. Many people need more rest during radiation therapy.

■      Sleep at least 8 hours each night.

■      Take short naps during the day. Nap for less than 1 hour at a time.

■      Read a book or listen to music to relax before going to bed at night.

Talk with your doctor or nurse if you still feel tired after trying these tips.

Questions to ask your doctor or nurse:

■      What can I do to feel less tired?

■      How long will this tired feeling last?

■      How much walking or light exercise should I do?

■      Is there medicine that could help? 

Loose stools (diarrhea)

What is diarrhea?

Do you have bowel movements more often than normal? Are they soft, loose, or watery? Then you may have diarrhea.

■  Call your doctor or nurse if you have diarrhea, stomach pain, or feel dizzy.

■  Ask about foods and medicine that can help.

Take these steps to feel better:

Drink more liquids each day.

Drinking will help you feel better. Although it won’t stop the diarrhea, it will help prevent dehydration (loss of too much water from the body).

■   Drink lots of clear liquids, such as water, ginger ale, and clear soup.

■   Most people who have diarrhea need to drink 8 to 12 cups of liquid each day. Ask your doctor or nurse how much you should drink.

Eat small meals that are easy on your stomach.

■   Eat small meals throughout the day, instead of 3 large meals.

■   Your doctor or nurse may suggest the BRAT foods. BRAT stands for: Bananas,

Rice, Applesauce, Toast

Limit or avoid foods and drinks that can make your diarrhea worse.

■   Don’t eat spicy, greasy, or fried foods.

■   Don’t have milk or dairy products such as cheese or ice cream. Check food labels to see if milk products are listed.

■   Don’t have drinks with caffeine or alcohol.

■   You may need to avoid or have less raw fruit, vegetables, and whole wheat breads and cereals.

■   Ask your doctor or nurse what foods you may need to avoid.

Taking care of your bottom (rectal area):

■   Use a baby wipe that is alcohol free and unscented.

■   It may help to sit in a shallow, warm bath (sitz bath).

■   Let your doctor or nurse know if your rectal area is sore or bleeds.

Questions to ask your doctor or nurse:

■    What problems should I call you about?

■    How much liquid should I drink each day?

■    What foods and drinks should I limit or avoid?

■   What are oral rehydration solution drinks? Where can I ind them?

■    What is a sitz bath? Should I take these?

■   What products can I use if my bottom is sore or bleeds? What should I not use?

Changes when you urinate

Radiation therapy can irritate the bladder and urinary tract. The discomfort usually goes away a few weeks after treatment is finished.

Call your doctor or nurse if you have a fever of 100.5° F (38° C) or higher.

Tell your doctor or nurse if you have any of these changes:

■   Pain, cramps, or a burning feeling when you urinate

■   A reddish color or blood in your urine

■   Trouble starting to urinate

■   Trouble getting all the urine out

■   A feeling that you have to urinate right away

■   Leaking a little urine when you sneeze or cough

Drink more liquids.

■   Drink lots of liquids each day. Drink enough so that your urine is clear to light yellow in color.

■   Water, cranberry juice, gelatin, and most soups are all good choices.

■   Keep track of how much you drink. Talk with your doctor or nurse to make sure you are drinking enough each day.

Ask about drinks or foods that you may need to avoid.

Some things can make these problems worse. Your doctor or nurse may suggest that you limit or don’t have:

■   Drinks with alcohol (such as beer, wine, and liquor)

■   Drinks with caffeine (such as coffee and black tea)

■   Drinks that are carbonated (such as sodas and colas)

■   Spicy foods

■   Tobacco products

Questions to ask your doctor or nurse:

·       What changes am I likely to have?

·       What problems should I call you about?

·       How long might these problems last?

·       Are there medicines, exercises, or other steps I can take to feel better?

·       How much liquid should I drink each day?

·       Are there any drinks or foods that I should avoid?


CHEMOTHERAPY

A 14-year study The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies published in Clinical Oncology in 2004 explored the contribution of cytotoxic chemotherapy to five year survival in 250 000 adults with solid cancers from Australian and US randomised trials. An important effect was shown on five year survival only in testicular cancer (40%), Hodgkin’s disease (37%), cancer of the cervix (12%), lymphoma (10.5%), and ovarian cancer (8.8%). Together, these represented less than 10% of all cases. In the remaining 90% of patients—including those with the commonest tumours of the lung, prostate, colorectum, and breast—drug therapy increased five year survival by less than 2.5%—an overall survival benefit of around three months.
Study Results:
The overall contribution of curative and adjuvant cytotoxic chemotherapy to 5-year survival in adults was estimated to be 2.3% in Australia and 2.1% in the USA.
Study Conclusion:
As the 5-year relative survival rate for cancer in Australia is now over 60%, it is clear that cytotoxic chemotherapy only makes a minor contribution to cancer survival…

Study Authors:
Graeme Morgan, Department of Radiation Oncology, Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, NSW;
Robyn Ward, Department of Medical Oncology, St Vincent’s Hospital, Sydney, NSW;
Michael Barton, Collaboration for Cancer Outcomes Research and Evaluation, Liverpool Health Service, Sydney, NSW, Australia
Read the full article in PubMed


NEW 2019

Breast Cancer drugs Paclitaxel and Herceptin can cause fatal lung disease.

On 16 July, 2019, The Worthing Herald reported on the case  Cecilia Francis, known as Celia, died at Worthing Hospital from lung disease induced by the chemotherapy drugs paclitaxel and herceptin, which she was given as ‘add-on’ treatment for breast cancer, on October 28 last year.

An inquest into her death, held at Crawley Coroner’s Court on Friday, July 12, heard that the 61-year-old of Furzeholme, Worthing, had not been informed that pnemonitis, an inflammation of the lungs, was a potentially life-threatening side effect of these drugs in the literature from cancer charities that she was given at hospital.

This 2017 study shows that Paclitaxel promotes the spread of cancer cells to the lungs.

One dose of 5-FU chemotherapy can kill you if you have a DPD enzyme deficiency. 

5-FU (5-fluorouracil) includes the following brand names:
Adrucil
Carac Tolak
Efudex
Fluoroplex
Xeloda (Capecitabine)

This meta-analysis  published in 2019 by The American College of Cardiology, reported that cardiovascular disease symptoms and heart attacks were observed in as little as 12 hours of intravenous infusions of 5-FU. Toxic reactions also include heart failure, seizures, and coma.

Dihydropyrimidine Dehydrogenase (DPD) is the liver enzyme largely responsible for deactivating and detoxifying more than 80% of 5-FU from the body. Without the DPD enzyme, fluorouracil-based drugs (5-FU and capecitabine) continue to poison the body indefinitely, resulting in overwhelming toxicity, collateral damage, and for some, agonizing death.

There is a blood test to check for the DPD enzyme deficiency, but most cancer patients are not given this test, or even told about it, before they are given 5-FU.

There is also an antidote to 5-FU poisoning called Vistoguard (uridine triacetate), but it must be given within 4 days, and it is very expensive.


New Study Delivers Another Black Eye for Chemotherapy

Article Source: GreenMedInfo.com
Saturday, July 8th 2017 at 3:45 pm

Written By:Jefferey Jaxen

chemotherapy spreads cancer

 

 

 

 

What if chemotherapy actually helped to spread cancer? Many within the medical and research communities are becoming emboldened to speak out against outdated and failed healing modalities still in use today.

UK Headlines were made in 2015 when a study in the British Journal of Cancer was published claiming 1 in 2 women and 1 in 3 men will develop cancer at some point in their lives. Two years later on June 20, 2017, a report titled Canadian Cancer Statistics 2017 released by the Canadian Cancer Society stated for males, the lifetime cancer risk is 49% and for females it is 45%.

Another study showing the dangers and ineffectiveness of chemotherapy has just been published and it has gone viral. The study titled Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism was published in the journal Science Translational Medicine describing how chemotherapy could allow cancer to spread, and trigger more aggressive tumors. By studying the process of intravasation, or entry of cells into the vasculature, the study’s authors discovered that chemotherapy, in addition to targeting tumor cells, can also increase intravasation. The authors found that chemotherapy increased groups of cells known as tumor microenvironment of metastasis (TMEM) which collectively usher tumor cells into the body’s vasculature. The study discovered that several types of chemotherapy can increase the amounts of TMEM complexes and circulating tumor cells in the bloodstream. Why is this important? The chances of survival dramatically decrease once cancer begins to metastasize through the bloodstream and effect other organs and systems.

Is the recent study the only one painting chemotherapy as a dangerous treatment option? In 2016 a groundbreaking study was commissioned by Public Health England and published in the journal Lancet Oncology. The study represented the first time that national data has been gathered together and analyzed for 30-day mortality after chemotherapy. It found that a larger proportion of patients are actually dying after chemotherapy than in the clinical trials carried out by the drug companies. The death rate in the clinical trials of drug treatments for lung cancer was 0.8%, but in the present study the reality shows it is actually 3%.

What happens when the extended survival rate of chemotherapy as a cancer treatment is studied beyond 30 days? An Australian study published in the journal Clinical Oncology found the contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies in adults was estimated to be 2.3% in Australia and 2.1% in the US. In fact, the study concluded by stating:

To justify the continued funding and availability of drugs used in cytotoxic chemotherapy, a rigorous evaluation of the cost-effectiveness and impact on quality of life is urgently required.

By now, many are beginning to understand that one of the problems with chemotherapy is that it doesn’t address the underlying cause(s) of cancer. Chemotherapy originated from an idea and consciousness that was far from idealistic. The whole generation of chemotherapeutic drugs that are being used today, and there are over one hundred of them, developed from poisonous nerve gas created for warfare. As reported in 2012 by Green Med Info, cancer is the second leading cause of death in the developed world, and yet much of the medical and research communities are still in the dark ages when it comes to treating and understanding it. However, in the age of information, great strides are being made by doctors and researchers who are going against the grain of the failed convention ‘wisdom’ in cancer treatment. In addition, individuals are beginning to take responsibility by educating themselves. GreenMedInfo has been at the forefront with the world’s most widely referenced, evidence-based natural medical resource database containing over 30,000 abstracts and articles.

© [Article Date] GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here http://www.greenmedinfo.com/greenmed/newsletter.


Chemo spill

Accidental Chemo spill

A study published in The Lancet (Sept. 2016)
30-day mortality after systemic anticancer treatment for breast and lung cancer in England: a population-based, observational study found:

Out of 28,364 patients with Breast Cancer who received Systemic Anticancer treatment (chemo), 700 died within 30 days of treatment start date.

Out of 15,045 patients with Lung Cancer who received Systemic Anticancer treatment, 1,274 died within 30 days of treatment start date.

Some of these patients died of disease progression or from other causes.

SACT = Systemic AntiCancer Treatment
Read the full article in Lancet Oncology

This study published in 2017 says chemotherapy “ may increase cancer cell dissemination and induce a more aggressive tumor phenotype with increased metastasis.”

Chemo can cause cancer to return
This study states:
Interestingly, rates of tumor cell repopulation have been shown to accelerate in the intervals between successive courses of treatment, and solid tumors commonly show initial responses followed by rapid regrowth and subsequent resistance to further chemotherapy. Our results indicate that damage responses in benign cells comprising the tumor microenvironment may directly contribute to enhanced tumor growth kinetics.

“Most cancer patients in this country die of chemotherapy. Chemotherapy does not eliminate breast, colon, or lung cancers. This fact has been documented for over a decade, yet doctors still use chemotherapy for these tumors.”
— Allen Levin, MD, UCSF — The Healing of Cancer

A look at five chemo (and other) drugs commonly given to cancer patients. The side-effects listed below are only a sample of the full range of side-effects observed. Please see individual manufacturers site for further details.


What causes cardiac toxicity?

Source: texas Oncology

There are many possible causes of cardiac toxicity. In cancer patients, cardiac toxicity may be caused by radiation to the chest and some chemotherapy drugs.

The most well-known cause of cardiac toxicity is the chemotherapy drug doxorubicin (Adriamycin®). Doxorubicin is a type of chemotherapy drug called an anthracycline. Anthracyclines may be used to treat leukemia, lymphoma, multiple myeloma and breast cancer. Other anthracyclines are:

  • Daunorubicin (Cerubidine®)
  • Epirubicin (Ellence®)
  • Idarubicin (Idamycin®)

Other chemotherapy drugs that may cause cardiac toxicity are:

  • Cyclophosphamide (Cytoxan®)
  • Fluorouracil (5-FU)
  • Mitoxantrone (Novantrone®)

Cancer drugs that have been reported to cause abnormalities in heart rate or rhythm in more than 10% of patients include:

  • Arsenic trioxide (Trisenox®)
  • Daunorubicin (Cerubidine®)
  • Denileukin diftitox (Ontak®)
  • Gemtuzumab ozogamicin (Mylotarg®)
  • Idarubicin (Idamycin®)
  • Melphalan (Alkeran®)
  • Octreotide (Sandostatin®)
  • Oprevelkin (Neumega®)
  • Paclitaxel (Taxol®)
  • Tretinoin (Vesanoid®)

Herceptin

Generic Name: Trastuzumab
Brand Names: Herceptin
Manufacturer: Roche

Condition or Diseases treated: Breast cancer

Information source: herceptin.com

Boxed WARNINGS and Additional Important Safety Information

Cardiomyopathyherceptin

  • Herceptin administration can result in sub-clinical and clinical cardiac failure. The incidence and severity was highest in patients receiving Herceptin with anthracycline-containing chemotherapy regimens

Infusion Reactions; Pulmonary Toxicity

  • Herceptin administration can result in serious and fatal infusion reactions and pulmonary toxicity. Symptoms usually occur during or within 24 hours of Herceptin administration.

Embryo-Fetal Toxicity

  • Exposure to Herceptin during pregnancy can result in oligohydramnios and oligohydramnios sequence manifesting as pulmonary hypoplasia, skeletal abnormalities, and neonatal death.

Cardiomyopathy

  • Herceptin administration can result in sub-clinical and clinical cardiac failure. The incidence and severity was highest in patients receiving Herceptin with anthracycline-containing chemotherapy regimens. In a pivotal adjuvant breast cancer trial, one patient who developed CHF died of cardiomyopathy
  • Herceptin can cause left ventricular cardiac dysfunction, arrhythmias, hypertension, disabling cardiac failure, cardiomyopathy, and cardiac death
  • Herceptin can also cause asymptomatic decline in LVEF

Infusion Reactions

  • Herceptin administration can result in serious and fatal infusion reactions
  • Infusion reactions consist of a symptom complex characterized by fever and chills, and on occasion include nausea, vomiting, pain (in some cases at tumor sites), headache, dizziness, dyspnea, hypotension, rash, and asthenia

Tamoxifen (Nolvadex)side effects Tamoxifen
Manufacturer: AstraZeneca
Condition or Diseases treated: Breast cancer
Information source Medicines.ie

Pregnancy. There have been a small number of reports of spontaneous abortions, birth defects and foetal deaths after women have taken Nolvadex, although no causal relationship has been established.

An increased incidence of endometrial cancer and uterine sarcoma (mostly malignant mixed Mullerian tumours) has been reported in association with Nolvadex treatment. The underlying mechanism is unknown, but may be related to the oestrogen-like effect of Nolvadex. Any patients receiving or having previously received Nolvadex, who report abnormal gynaecological symptoms, especially vaginal bleeding, should be promptly investigated.

A number of second primary tumours, occurring at sites other than the endometrium and the opposite breast, have been reported in clinical trials, following the treatment of breast cancer patients with tamoxifen. No causal link has been established and the clinical significance of these observations remains unclear.


Breast cancer patients initially treated with tamoxifen have a twofold increased risk of uterine corpus cancer, with particularly high risks seen for rare tumors of the mixed mullerian type.
Source: Second Cancers – Landmark Studies

Avastin (Bevacizumab)side effects avastin
Manufacturer: Roche Group
Condition or Diseases treated: Metastatic Colorectal Cancer
Information supplied by: Genentech USA

Possible serious side effects

Most serious side effects (not common, but sometimes fatal):
GI perforation
A hole that develops in your stomach or intestine. Symptoms include pain in your abdomen, nausea, vomiting, constipation, or fever
Wounds that don’t heal
A cut made during surgery can be slow to heal or may not fully heal.

Serious bleeding
This includes vomiting or coughing up blood; bleeding in the stomach, brain, or spinal cord; nosebleeds; and vaginal bleeding.

What are the other possible serious side effects?
% = Percentage of patients who had this side effect in clinical studies across different cancers

Severe high blood pressure 18%
Blood pressure that severely spikes or shows signs of affecting the brain.
Kidney problems 7%
These may be caused by too much protein in the urine and can sometimes be fatal
Infusion reactions 3%
Infusion reactions include high blood pressure or severe high blood pressure that
may lead to stroke
trouble breathing
decreased oxygen in red blood cells
a serious allergic reaction
chest pain
headache
tremors
excessive sweating.
Severe stroke or heart problems 2.6%
These may include blood clots, mini-stroke, heart attack, and chest pain.
These can sometimes be fatal
Abnormal passage in the body 2%
This type of passage—known as a fistula—is an irregular connection from one part of the body to another and can sometimes be fatal
Nervous system and vision problems 0.5%
Signs include headache, seizure, high blood pressure, sluggishness, confusion, and blindness

What are the side effects seen most often?
In clinical studies across different types of cancer, some patients experienced the following side effects:

  • High blood pressure
     
  • Too much protein in the urine
  • Nosebleeds
  • Rectal bleeding
  • Back pain
  • Headache
  • Taste change
  • Dry skin
  • Inflammation of the skin
  • Inflammation of the nose
  • Watery eyes

Afinitor (Everolimus)side effects AFINITOR
Manufacturer: Novartis

Condition or Diseases treated: Breast cancer
Information source: Novartis Pharmaceuticals Corporation

WARNINGS AND PRECAUTIONS

  • Non-infectious pneumonitis: Monitor for clinical symptoms or radiological changes; fatal cases have occurred.
  • Infections: Increased risk of infections, some fatal.
  • Renal failure: Cases of renal failure (including acute renal failure), some with a fatal outcome, have been observed.
  • Angioedema: Patients taking concomitant ACE inhibitor therapy may be at increased risk for angioedema.
  • Oral ulceration: Mouth ulcers, stomatitis, and oral mucositis are common.
  • Impaired wound healing: Increased risk of wound-related complications.
  • Laboratory test alterations:
    Elevations of serum creatinine, urinary protein, blood glucose, and lipids may occur. Decreases in hemoglobin, neutrophils, and platelets may also occur.
  • Embryo-Fetal Toxicity: Can cause fetal harm.

Alimta (Pemetrexed)side effects Alimta
Manufacturer: Eli Lilly
Condition or Diseases treated: Non-small cell lung cancer

Information Source: Eli Lilly

ALIMTA can suppress bone marrow function, which may cause low blood cell counts.

Call your doctor right away if you have a fever, chills, diarrhea, or mouth sores. These symptoms could mean you have an infection, which may be severe and could lead to death.

The most common side effects of ALIMTA when given alone or in combination with cisplatin are:

  • Stomach upset, including nausea, vomiting, diarrhea, or constipation.
  • Low blood cell counts:

    • Low red blood cells. Low red blood cells may make you feel tired, get tired easily, appear pale, and become short of breath.
    • Low white blood cells. Low white blood cells may give you a greater chance for infection.
    • Low platelets. Low platelets give you a greater chance for bleeding. Your doctor will do blood tests to check your blood counts before and during treatment with ALIMTA.
  • Tiredness. You may feel tired or weak for a few days after your ALIMTA treatments.
  • Redness or sores in your mouth, throat, on your lips, or in the tube that connects your throat and stomach (esophagus). You may get redness or sores in your mouth, throat, on your lips, or in your esophagus (stomatitis, pharyngitis, esophagitis) or you may feel pain or have difficulty when drinking or swallowing food. These symptoms may happen a few days after ALIMTA treatment.
  • Loss of appetite. You may lose your appetite and lose weight during your treatment.
  • Rash. You may get a rash or itching during treatment. These reactions usually appear between treatments with ALIMTA and usually go away before the next treatment. Skin reactions or rashes that include blistering or peeling may be severe and could lead to death. These are not all the side effects of ALIMTA. For more information, ask your doctor, nurse, or pharmacist.

Zoladex (Goserelin acetate)side effects Zoladex
Condition or Diseases treated: Prostate cancer
Information supplied by: Drugs.com

  • Cardiovascular Diseases:
    Increased risk of myocardial infarction, sudden cardiac death and stroke has been reported in association with use of GnRH analogs in men.

Less common:

  • Fast or irregular heartbeat

Rare

  • Bone, muscle, or joint pain
  • changes in skin color of the face
  • fainting
  • fast or irregular breathing
  • numbness or tingling of the hands or feet
  • puffiness or swelling of the eyelids or around the eyes
  • skin rash, hives, or itching
  • sudden, severe decrease in blood pressure and collapse
  • tightness in the chest
  • troubled breathing
  • Pain in the chest
  • pain in the groin or legs (especially in the calves of the legs)

Minor Side Effects

More common:

  • Sudden sweating and feelings of warmth (also called hot flashes)

Less common:

  • Blurred vision
  • burning, itching, redness, or swelling at the place of injection
  • decreased interest in sexual intercourse
  • dizziness
  • headache
  • nausea or vomiting
  • swelling and increased tenderness of the breasts
  • swelling of the feet or lower legs
  • trouble sleeping
  • weight gain

Less common:

  • Bone pain
  • constipation
  • decreased size of the testicles
  • inability to have or keep an erection

For a full list of all your treatment options please see Treatment Options

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