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Bone Cancer

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General Information About Osteosarcoma and Malignant Fibrous Histiocytoma of Bone

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PQQ (Pyrroloquinoline quinone)
PQQ is a natural compound found in a variety of foods. It acts as an antioxidant and supports healthy mitochondrial function.

This study says: Chondrosarcoma is the second most commonly occurring primary bone malignancy, which affects the pelvis, long bones and the spine, in addition to the larynx, head and neck, and it eventually metastasizes. Currently, chondrosarcoma remains largely incurable due to poor prognosis and a high rate of recurrence.The present study examined cell death following treatment with or without different concentrations of PQQ in cancer and normal cells. It was identified that cell death increased in a dose- and time-dependent manner following treatment with PQQ, while the effect on normal cells was relatively small.

In conclusion, the mechanism underlying PQQ-induced apoptosis may be associated with increasing the levels of ROS, suggesting that PQQ may be a potential drug for chondrosarcoma therapies.

Widely available as a supplement.


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